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Amy K Fewell | Homesteading for the Kingdom

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The Science of Herbs and How They Work

July 29, 2025 · In: herbs

When I first began my herbal medicine journey, I was much like everyone else. I began doing research online, googling things like “herbs for headaches”, and thinking I knew a lot about herbs simply from my own online research. When you try to implement these findings into your daily life, however, you may find that just knowing that one herb can be used for a certain symptom, yet you don’t understand why it works, causes more confusion than healing. When we don’t understand how herbs and their botanical compounds work, we do ourselves a disservice. 

There are many herbs that can support one symptom that your body is having, but which one is the best? How exactly does the chemical makeup of herbs interact with the human body? What are the properties of these plant chemicals? This is where we start learning about pharmacognosy, and it is an integral part of holistic learning.

The American Society of Pharmacognosy defines pharmacognosy as “the study of the physical, chemical, biochemical, and biological properties of drugs, drug substances, or potential drugs, or potential drug substances of natural origin, as well as the search for new drugs from natural sources.”

Broken down into an easier to understand definition—pharmacognosy defines and teaches us about the physical, chemical, and other properties and actions of herbs and plants, and how they work. Chemical groups and families within herb substances have actions that can be generalized. There are some botanical components you should know about when it comes to the chemical actions of herbs and how they work with the human body. Knowing how herbs work will help you choose the best options that are needed for an ailment, disease, or symptom. It especially helps you when studying a new plant in the wild. 

While generalized definitions of these chemicals and actions make it easy, we should never confine these herbs only to these generalized actions. As you dive further into your herbal education in this book, you’ll understand more confidently how they work together, not just independently, as well.

Once you feel confident in knowing the pharmacognosy aspect of herbs, from there you may be better able to understand pharmacokinetics. Pharmacokinetics (sometimes abbreviated PK) is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism. It is the branch of pharmacology concerned with the movement of drugs or substances within the body—absorption, distribution, metabolism, and excretion. Essentially, how does this herb or remedy work in the body most efficiently, and what does the body do with the herb or remedy once it has been distributed and metabolised? Are all herbs excreted immediately, or are some reabsorbed? Let’s find out. 

Let’s pull pharmacognosy and pharmacokinetics together. First, let’s look at the chemical compounds of herbs—pharmacognosy.

This article is part of the Homestead Herbalist Membership Plan on my substack. Subscribe HERE.

By: Amy K. Fewell · In: herbs · Tagged: herbs

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I'm Amy. I love organic food but I love cookies too. I love Jesus and His grace. I believe broken people make the biggest impact in the world when Jesus makes them whole, and when they share their stories. I believe in stories, and I'm sharing mine.

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@amy.fewell

This… This…
Day 485 of healing my body after baby number 4. It Day 485 of healing my body after baby number 4. It’s a journey, especially running on 3-4 hours of sleep every night with only a partially weaned baby. But, nevertheless, it is. Thankfully I can support my body through it, and you can too! 

This nourishing herbal infusion brings together herbs that support the body through stress, hormonal changes, inflammation, and digestive discomfort.

I add ½ to 1 tablespoon of each dried herb to my infusion teapot, pour hot water over the herbs, cover, and allow them to steep before straining. You can drink 2-3 cups per day. This little tea pot makes about 3 normal sized coffee cupfuls of tea.

• Rose supports the nervous system, uplifts the mood, and gently nourishes the heart and reproductive tissues during hormonal transitions.

• Stinging nettle provides nutrient-rich support with iron, calcium, magnesium, and other trace minerals important to the endocrine system.

• Lemon balm calms stress-related tension while supporting healthy digestion, mood, sleep, and thyroid function.

• Peach leaf is traditionally used as a cooling, moistening herb for heat, irritation, nausea, and nervous tension that may accompany hormonal changes.

• Turmeric supports a healthy inflammatory response, liver function, digestion, and the body’s metabolism and elimination of hormones.

• Peppermint cools excess heat and supports digestion, liver function, mental clarity, and relief from occasional nausea or headaches.

This is a beautiful example of how herbs can nourish multiple systems at once—the nervous, digestive, endocrine, and reproductive systems—while also supporting the body’s foundational nutritional needs.
In a world that is increasingly fake, uniqueness a In a world that is increasingly fake, uniqueness and the ability to be known by something deeply personal, such as your name, is important. This seal says “House of Fewell”. Because as we move into the times ahead, you’ll be known in your community by which “house” you’re from (I’ll write about this more soon). Not just your family name, but the house of Yahweh. 

So, I thought I’d start a new family tradition. Bring back the signet and wax seals.
Two people can both tell you they have “poor circu Two people can both tell you they have “poor circulation” and need completely different herbal approaches.

One may be pale, chilly, sluggish, have cold hands and feet, prefer warm food, and feel considerably better when the weather warms.

Another may flush easily, run hot, dislike summer heat, become restless when overheated, and notice inflammatory complaints worsening with warmth.

The complaint may be the same, but the pattern is not.

In traditional Western herbalism, Heat/Excitation represents excessive activity. We may observe warmth, redness, flushing, irritation, restlessness, a more active pulse, and blood tending toward the surface.

The herbal direction may include cooling, calming, relaxing, or moderating herbs such as yarrow, rose, lemon balm, hibiscus, hawthorn, and elderflower.

Cold/Depression represents insufficient activity. We may see pallor, cold hands and feet, sluggish peripheral circulation, low energy, slower digestion, worsening with cold, and improvement with warmth or movement.

Here we may consider warming and stimulating herbs such as ginger, cayenne, rosemary, cinnamon, angelica, and historically sassafras.

But this is where herbalism requires more than matching symptoms to herbs.

Cold hands do not automatically mean Cold/Depression. Tension and constriction can also restrict blood flow to the extremities. Likewise, heat can exist alongside stagnation.

One symptom does not make a tissue state.

Instead of asking:
“What herb improves circulation?”

Ask:
"What is the blood actually doing—and why?"

Is the person hot or cold? Tense or relaxed? Stagnant or moving freely? Dry or damp? Depleted or robust?

Once we understand the direction of the pattern, we can begin choosing herbs much more intelligently.

Part Two of my "State of the Blood" series is now available inside the Homestead Herbalist membership.

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